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Necropsy | Mammalian, Avian and Aquatic Histology Avian and Aquatic Pathology EPL has expertise in the post-mortem diagnostic evaluation of many aquatic animal species. Among these are laboratory animals used for toxicologic testing, and wild species that are collected in order to evaluate the effects of xenobiotics on organisms in natural waterways. Typical aquatic animals used in laboratory experiments include small aquarium fishes such as Japanese medaka, guppies, zebrafish, and fathead minnows, and amphibians such as the leopard frog and the African clawed frog. Animals evaluated in survey studies include numerous species of freshwater and marine fish. Examples of xenobiotics featured in EPL studies include polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), by-products of chlorination of water supplies, therapeutic antimicrobials, and a variety of chemicals that interfere with endocrine balance and thus impair reproductive processes. EPL Aquatic Animal Services
Special Aquatic Animal Pathology
People Drs. Marilyn Wolfe and Jeffrey Wolf participate in aquatic field and laboratory studies. Both are Diplomates of the American College of Veterinary Pathologists and hold memberships in numerous scientific organizations concerned with pathology, fish health, and environmental toxicology. Dr. Marilyn Wolfe has been involved in aquatic animal pathology since 1985. She was one of several authors of a book chapter on the preparation of whole small fish for histological evaluation. Dr. Wolfe has long been a pioneer in the development of techniques for the diagnostic evaluation of toxicologic effects in small aquarium fishes such as medaka. Dr. Jeffrey Wolf has been involved in aquatic animal pathology since 1995. From 1996 through 1999, Dr. Wolf was the primary diagnostician in the Aquatic Medicine Laboratory at the Virginia-Maryland Regional College of Veterinary Medicine. He has co-authored a book chapter on zoonotic disease of fish and shellfish and has been involved in the preparation of guidelines for international studies involving environmentally relevant chemicals implicated as endocrine disruptors. They have both collaborated on numerous projects involving fish and amphibians, have given presentations on fish topics at regional and national scientific meetings, have provided expertise at fish pathology workshops, and are the Principal Investigator and Co-principal Investigator, respectively, of the National Cancer Institute's Registry of Tumors in Lower Animals. |
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