Services: Toxicologic Pathology

Necropsy | Mammalian, Avian and Aquatic Histology
Mammalian Pathology | Avian and Aquatic Pathology

Avian and Aquatic Pathology

EPL has expertise in the post-mortem diagnostic evaluation of many aquatic animal species.  Among these are laboratory animals used for toxicologic testing, and wild species that are collected in order to evaluate the effects of xenobiotics on organisms in natural waterways.  Typical aquatic animals used in laboratory experiments include small aquarium fishes such as Japanese medaka, guppies, zebrafish, and fathead minnows, and amphibians such as the leopard frog and the African clawed frog.  Animals evaluated in survey studies include numerous species of freshwater and marine fish.  Examples of xenobiotics featured in EPL studies include polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), by-products of chlorination of water supplies, therapeutic antimicrobials, and a variety of chemicals that interfere with endocrine balance and thus impair reproductive processes. 

EPL Aquatic Animal Services

  • Gross Necropsy of Aquatic Animals
  • Diagnostic Histopathology of Fishes, Amphibians, and Aquatic Invertebrates
  • Toxicologic Histopathology of Fishes, Amphibians, and Aquatic Invertebrates
  • Consultation in Controlled Study Design,  Laboratory and Field

Special Aquatic Animal Pathology

  • Histomorphometry/Image Analysis
  • Digital Imaging
  • Immunohistochemistry
  • Reproductive Pathology
  • Electron Microscopy (TEM/SEM)

People

Dr. Jeffrey Wolf participates in aquatic field and laboratory studies. He is a Diplomate of the American College of Veterinary Pathologists and holds memberships in numerous scientific organizations concerned with pathology, fish health, and environmental toxicology.  Dr. Wolf has been involved in aquatic animal pathology since 1995.  From 1996 through 1999, Dr. Wolf was the primary diagnostician in the Aquatic Medicine Laboratory at the Virginia-Maryland Regional College of Veterinary Medicine.  He has co-authored a book chapter on zoonotic disease of fish and shellfish and has been involved in the preparation of guidelines for international studies involving environmentally relevant chemicals implicated as endocrine disruptors.   He has collaborated on numerous projects involving fish and amphibians with representatives of industry, government, and envirnomental groups, has given presentations involving aquatic animals at regional and national scientific meetings, and is a co-editor for the Journal of Aquatic Animal Health and an associate editor for Toxicologic Pathology."
Histologic diagnosis of avian and aquatic species includes corals and amphibians.
Histologic diagnosis of avian and aquatic species includes corals and amphibians.
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