Category: Safety Assessment

EPL, Inc. Opens a Northeast Office in Collegeville, Pennsylvania

Experimental Pathology Laboratories, Inc. (EPL®) established EPL Northeast on February 8, 2016. This office is headed by Dr. Heath Thomas who was formerly Vice President of Safety Assessment at GlaxoSmithKline. The Northeast office is located outside of Philadelphia at 125 Chinaberry Lane, Collegeville, PA. With this location, Dr. Thomas will be able to provide local […]

DiscoveryPathologySafety AssessmentToxicology

Meet Aclairo Pharmaceutical Development Group

Imagine a group of great scientists and all around nice folks who worked with another group for years in dovetailed projects for their clients. It does not take much imagination to wonder why these folks would want to be in one happy group together.  On January 1, 2016, EPL, Inc.  acquired Aclairo PDG, Inc. as […]

Clinical Pharmacology & ModelingDiscoverySafety AssessmentToxicology

Experimental Pathology Laboratories, Inc. (EPL) Acquires Aclairo Pharmaceutical Development Group, Inc.

EPL and Aclairo Combine Preclinical Services Expertise EPL is pleased to announce that it has acquired Aclairo Pharmaceutical Development Group, Inc. (Aclairo) which provides independent and objective nonclinical, regulatory, and clinical ADME/DMPK expert strategy and implementation to the pharmaceutical and drug device industries. “Aclairo’s team of industry and ex-FDA experts have developed a specialized consultancy […]

Clinical Pharmacology & ModelingHistologySafety AssessmentToxicology

On-Time Pathology Reporting

It is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed.  Most situations are readily managed, but in rare […]

HistologyPathologySafety AssessmentToxicology

EPL Clinical Pathology Evaluation and Consultation Services

Experimental Pathology Laboratories, Inc. (EPL) is pleased to announce that Dr. Valerie Barlow will be providing clinical pathology evaluation and consultation services for EPL. Dr. Valerie G. Barlow holds a DVM, a Master of Science and Ph.D., and is a Diplomate of the American College of Veterinary Pathologists (clinical pathology).  Dr. Barlow was born and […]

PathologySafety AssessmentToxicology

The Benefits of Immunohistochemistry (IHC)

Immunohistochemistry (IHC) has become a routinely used methodology for investigative and diagnostic evaluations that utilizes antigen-antibody reactions to identify antigens within cells or tissues.  While antigens are usually proteins, other antigenic biological products can also be recognized by antibodies including carbohydrates, lipids, nucleic acids, and others.   The identification and localization of tissue antigens using IHC […]

Biological TestingDiscoveryHistologyPathologySafety Assessment

EPL, Inc. Opens a Midwest Office in West Lafayette, Indiana

Experimental Pathology Laboratories, Inc. (EPL) opened a Midwest facility on September 1, 2014.  This office is headed by Dr. Paul Snyder formerly a Professor at Purdue University.  The Midwest office is located in the Purdue Research Park at 1305 Cumberland Ave., West Lafayette, IN.  With this central location, Dr. Snyder will be able to provide local […]

DiscoveryPathologyResearch ModelsSafety AssessmentToxicology

Evolving Roles of the Toxicologic Pathologist in Multi-disciplinary Research

The role of the toxicologic pathologist is continuously evolving and becoming ever more complex, as novel tools are being developed to identify structural and biochemical changes that result from exposure to toxic substances, and elucidate mechanisms of action by which toxins may potentially impact animal and human health.  Recently, EPL has been working with ToxStrategies […]

DiscoveryPathologyResearch ModelsSafety AssessmentToxicology

Ocular Toxicity Studies: Specialized Necropsy, Histology, and Pathology Methods

The eye and the ocular adnexa are common target organs in toxicology studies, but the appropriate evaluation of ocular tissues is a specialized endeavor.  Compared to routine toxicity studies, ocular toxicity studies require methodological modifications at almost every stage from study design to the final pathology report. For example, at necropsy, the fragile nature of […]

HistologyPathologySafety AssessmentToxicology