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Reading Time: 5 minutesIn toxicologic pathology, “blind slide reading” involves procedures in which the pathologist is unaware of the treatment group status of individual animals during the histologic slide evaluation phase of a toxicologic bioassay.  Blind slide reading continues to be a controversial topic, despite published recommendations on this subject authored by professional societies and governmental regulatory agencies […]

Reading Time: 2 minutesDr. Jim Fikes joins Experimental Pathology Laboratories, Inc. (EPL) as a Senior Pathologist and Manager of EPL-Boston, MA.  Dr. Fikes will be responsible for the pathology phases of commercial client’s various toxicology studies to include consultation services, initial histopathology evaluation, pathology peer review, and either participating, organizing, or conducting pathology working groups.  Dr. Fikes has

Reading Time: 2 minutesDr. Elizabeth Galbreath joins Experimental Pathology Laboratories, Inc. (EPL) as a Senior Pathologist and Manager of EPL-Boston, MA.  In addition, Dr. Galbreath will be available as a Principal Consultant for Aclairo Pharmaceutical Development Group Inc, an EPL company. Dr. Galbreath will be available to integrate with a client’s preclinical study efforts to provide consultation services in

Reading Time: 5 minutesIn toxicologic pathology, “blind slide reading” involves procedures in which the pathologist is unaware of the treatment group status of individual animals during the histologic slide evaluation phase of a toxicologic bioassay.  Blind slide reading continues to be a controversial topic, despite published recommendations on this subject authored by professional societies and governmental regulatory agencies

Reading Time: 2 minutesEPL’s experience with and use of whole slide images dates to the early 2000s. Our digital imaging technicians are dedicated to capturing your slides as the best digital surrogates to meet your consultation, educational, digital peer review, or quantitative analysis* needs. Our VA and NC locations provide high-throughput whole slide imaging services to our clients

Reading Time: 3 minutesStereology is a tool for obtaining unbiased estimates of object numbers and/or sizes within three-dimensional regions of interest.  For biological samples, quantitative measurements are potentially more objective and accurate when compared to traditional semi-quantitative grading of findings by pathologists (i.e., scoring of morphologic changes as minimal, mild, moderate, or severe).  Although both approaches require high

Reading Time: 4 minutesImmunohistochemistry or Immunofluorescence (IHC/IF) is employed routinely for investigative and diagnostic evaluations of antigen-antibody interactions within cells or tissues. While most IHC/IF target antigens are proteins, other antigenic biological substrates can also be recognized by antibodies (e.g., carbohydrates, lipids, or nucleic acids). Accurate and reproducible results are achieved when procedures used to identify and localize

Reading Time: 2 minutesWith the processing of up to 50,000 tissues per month, and projects regularly flowing in and out of our labs, histology scheduling at EPL is a continual process. Recognizing that the project timeline, in addition to quality and expertise, is one of the most important factors to our clients, we’re providing the following tips on the items

Reading Time: 3 minutesExperimental Pathology Laboratories, Inc. (EPL) meets or exceeds current FDA guidelines following the release of “Pathology Peer Review in Nonclinical Studies: Questions and Answers, Guidance for Industry” document in December 2021 (https://www.fda.gov/media/129533/download) At EPL we pride ourselves on providing our clients with not only the best services possible, but also with the up to the

Reading Time: 3 minutesMeet EPL and Aclairo at the 38th Annual ACT in Booth #200 Members of EPL, Inc. and Aclairo Pharmaceutical Development Group, Inc. will attend the 2017 38th Annual meeting of the American College of Toxicology held at the Palm Springs Convention Center – 277 N. Avenida Caballeros –Palm Springs, CA 92262.  Register for ACT Join EPL at Our Hosted Program: “All About