Category: Toxicology
Blind Slide Reading
In toxicologic pathology, “blind slide reading” involves procedures in which the pathologist is unaware of the treatment group status of individual animals during the histologic slide evaluation phase of a toxicologic bioassay. Blind slide reading continues to be a controversial topic, despite published recommendations on this subject authored by professional societies and governmental regulatory agencies […]
Immunostaining Assay Optimization – Tackling Intrinsic Study Variables
Immunohistochemistry or Immunofluorescence (IHC/IF) is employed routinely for investigative and diagnostic evaluations of antigen-antibody interactions within cells or tissues. While most IHC/IF target antigens are proteins, other antigenic biological substrates can also be recognized by antibodies (e.g., carbohydrates, lipids, or nucleic acids). Accurate and reproducible results are achieved when procedures used to identify and localize […]
Pathology Peer Review
Experimental Pathology Laboratories, Inc. (EPL) meets or exceeds current FDA guidelines following the release of “Pathology Peer Review in Nonclinical Studies: Questions and Answers, Guidance for Industry” document in December 2021
Meet EPL and Aclairo at the 38th Annual ACT in Booth #200
Meet EPL and Aclairo at the 38th Annual ACT in Booth #200 Members of EPL, Inc. and Aclairo Pharmaceutical Development Group, Inc. will attend the 2017 38th Annual meeting of the American College of Toxicology held at the Palm Springs Convention Center – 277 N. Avenida Caballeros –Palm Springs, CA 92262. Register for ACT Join EPL at Our Hosted Program: “All About […]
Meet EPL and Aclairo at the SOT 57th Annual Meeting
Meet the professionals from EPL and Aclairo at the SOT 57th Annual Meeting and ToxExpo in San Antonio, Texas from March 11-15 in Booth #922. Register Now https://gallery.mailchimp.com/ac4f9b280cf9318f92a974f7f/images/2bae830e-b513-490d-b566-0d81955f4d5a.png https://gallery.mailchimp.com/ac4f9b280cf9318f92a974f7f/images/ddd85845-8d13-4be5-8019-c58db4a108b9.png About EPLFounded in 1971, Experimental Pathology Laboratories, Inc. (EPL®) is a private, employee-owned U.S. company that is recognized internationally for its ability to meet the needs of the scientific community and the […]
Experimental Pathology Laboratories, Inc. Announces a Strategic Alliance with Quality Scientific Solutions, LLC
Experimental Pathology Laboratories, Inc. (EPL) announces a new strategic alliance with Quality Scientific Solutions, LLC (QS3). This alliance is targeted to provide EPL’s preclinical pathology expertise as an important resource to QS3. About Quality Scientific SolutionsQuality Scientific Solutions, LLC is a research and consulting company dedicated to helping clients create products that meet the highest standard […]
EPL – Independent and Employee-Owned
Experimental Pathology Laboratories, Inc. (EPL) is an independent, private, employee-owned company that is recognized internationally for its ability to meet the needs of the scientific community and the challenges of preclinical safety testing and development with high quality histopathology services. EPL was founded in 1971, and became an employee-owned company in 1992. EPL is proud […]
Aclairo Welcomes Dr. Heath Thomas as New President
Experimental Pathology Laboratories, Inc. (EPL) and Aclairo Pharmaceutical Development Group, Inc. (Aclairo) are excited to announce that Dr. Heath Thomas has joined Aclairo as President and Senior Consultant. Dr. Thomas is a board-certified veterinary pathologist with over 20 years of experience in drug development from time spent with SmithKline Beecham, DuPont Pharmaceuticals, and GlaxoSmithKline, as […]
Using Transmission Electron Microscopy in Preclinical Safety Studies
The use of Transmission Electron Microscopy (TEM) in preclinical studies has significantly waned in the last 20 or so years. There are multiple reasons for this. TEM is expensive and labor intensive. Compared to standard histopathology, TEM requires significantly more time and money to analyze samples. The cost of maintaining an electron microscope is practical […]
On-Time Pathology Reporting
It is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed. Most situations are readily managed, but in rare […]