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Reading Time: 2 minutesThe eye and the ocular adnexa are common target organs in toxicology studies, but the appropriate evaluation of ocular tissues is a specialized endeavor.   Compared to routine toxicity studies, ocular toxicity studies require methodological modifications at almost every stage from study design to the final pathology report. EPL has extensive experience in the processing and […]

Reading Time: 2 minutesStereology is a tool for obtaining unbiased estimates of object numbers and/or sizes within three-dimensional regions of interest.  For biological samples, quantitative measurements are potentially more objective and accurate when compared to traditional semi-quantitative grading of findings by pathologists (i.e., scoring of morphologic changes as minimal, mild, moderate, or severe).  Although both approaches require high

Reading Time: 2 minutesCompanies who outsource the histopathology component of their valuable studies need to know that the work will be performed to the highest quality standards, on time, and at competitive prices.  Although claims of quality are easily made, true quality can be a difficult metric to gauge.  So let’s look at the evidence. Unlike its few

Reading Time: < 1 minuteEPL is pleased to announce the promotion of Dr. Kathleen Funk to President of EPL on June 1, 2016.  Dr. Funk has served as the Chief Operating Officer since 2014.  Dr. Funk is a graduate of the Virginia-Maryland Regional College of Veterinary Medicine and also holds a PhD in Comparative Pathology from the University of

Reading Time: 2 minutesEPL announces a newly formed strategic alliance with Histion, an Everett, Washington based preclinical laboratory specializing in GLP-compliant routine and specialty histology and evaluation services.  This alliance is specifically targeted to expand and enhance EPL’s and Histion’s capabilities to an ever expanding area of medical device and novel biomaterial testing.  Although Histion specializes in processing

Reading Time: 3 minutesExperimental Pathology Laboratories, Inc. (EPL®) established EPL Northeast on February 8, 2016. This office is headed by Dr. Heath Thomas who was formerly Vice President of Safety Assessment at GlaxoSmithKline. The Northeast office is located outside of Philadelphia at 125 Chinaberry Lane, Collegeville, PA. With this location, Dr. Thomas will be able to provide local

Reading Time: < 1 minuteImagine a group of great scientists and all around nice folks who worked with another group for years in dovetailed projects for their clients. It does not take much imagination to wonder why these folks would want to be in one happy group together.  On January 1, 2016, EPL, Inc.  acquired Aclairo PDG, Inc. as

Reading Time: < 1 minuteEPL and Aclairo Combine Preclinical Services Expertise EPL is pleased to announce that it has acquired Aclairo Pharmaceutical Development Group, Inc. (Aclairo) which provides independent and objective nonclinical, regulatory, and clinical ADME/DMPK expert strategy and implementation to the pharmaceutical and drug device industries. “Aclairo’s team of industry and ex-FDA experts have developed a specialized consultancy

Reading Time: 3 minutesIt is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed.  Most situations are readily managed, but in rare

Reading Time: 3 minutesA quality histological slide contains tissue that was properly sampled, fixed, processed, embedded, microtomed, and stained without artifacts. The production of a quality slide requires that work be conducted according to the highest standards during each phase of histologic processing. The first and most important steps are precise necropsy techniques (e.g., postmortem interval, tissue sample