Reading Time: < 1 minutePlease help spread the word about these recent articles highlighting the Best Practices and Contemporary Approaches to Nonclinical Pathology Evaluation of Medical Devices!
Nonclinical Pathology Evaluation of Medical Devices? Read More »
Reading Time: 5 minutesBlind slide reading is widely discussed in toxicologic pathology. Learn why experienced pathologists often use a two-phase approach—initial unblinded evaluation followed by blinded confirmation—to balance detection of subtle findings with avoidance of bias.
Blind Slide Reading Read More »
Reading Time: 2 minutesExperimental Pathology Laboratories (EPL) welcomes Dr. Jim Fikes as Senior Pathologist and Manager of EPL-Boston. A board-certified veterinary pathologist and toxicologist with more than 30 years in biopharmaceutical research, Dr. Fikes brings deep expertise in toxicologic pathology, histopathology evaluation, pathology peer review, and nonclinical safety assessment across pharmaceutical and biotechnology development programs.
Experimental Pathology Laboratories, Inc. Welcomes Dr. Jim Fikes! Read More »
Reading Time: 2 minutesExperimental Pathology Laboratories (EPL) welcomes Dr. Elizabeth Galbreath as Senior Pathologist and Manager of EPL-Boston. A board-certified veterinary pathologist with more than 25 years in biopharmaceutical research and development, Dr. Galbreath brings extensive expertise in toxicologic and investigative pathology, neuropathology, pathology peer review, and preclinical development strategy for complex biotherapeutic and gene therapy programs.
Elizabeth J. Galbreath, DVM, PhD, DACVP – Senior Pathologist, Manager EPL-Boston, MA Read More »
Reading Time: 2 minutesExperimental Pathology Laboratories provides high-throughput whole slide imaging services using advanced digital pathology technologies. With decades of experience, EPL supports consultation, peer review, education, and quantitative analysis through high-quality digital slide capture and secure image sharing for clients worldwide.
EPL’s Whole Slide Imaging Services Read More »
Reading Time: 2 minutesStereology provides unbiased, quantitative measurements of structures within biological tissues. This article explains how design-based stereological methods improve accuracy compared to traditional grading approaches and describes their applications in toxicologic pathology and nonclinical safety studies.
Stereology: Probing for Precision Read More »
Reading Time: 4 minutesImmunohistochemistry or Immunofluorescence (IHC/IF) is employed routinely for investigative and diagnostic evaluations of antigen-antibody interactions within cells or tissues. While most IHC/IF target antigens are proteins, other antigenic biological substrates can also be recognized by antibodies (e.g., carbohydrates, lipids, or nucleic acids). Accurate and reproducible results are achieved when procedures used to identify and localize
Immunostaining Assay Optimization – Tackling Intrinsic Study Variables Read More »
Reading Time: 2 minutesWith the processing of up to 50,000 tissues per month, and projects regularly flowing in and out of our labs, histology scheduling at EPL is a continual process. Recognizing that the project timeline, in addition to quality and expertise, is one of the most important factors to our clients, we’re providing the following tips on the items
How to Ensure the Quickest Possible Histology Project Timeline Read More »
Reading Time: 3 minutesExperimental Pathology Laboratories, Inc. (EPL) meets or exceeds current FDA guidelines following the release of “Pathology Peer Review in Nonclinical Studies: Questions and Answers, Guidance for Industry” document in December 2021 (https://www.fda.gov/media/129533/download) At EPL we pride ourselves on providing our clients with not only the best services possible, but also with the up to the
Pathology Peer Review Read More »
Reading Time: 3 minutesMeet EPL and Aclairo at the 38th Annual ACT in Booth #200 Members of EPL, Inc. and Aclairo Pharmaceutical Development Group, Inc. will attend the 2017 38th Annual meeting of the American College of Toxicology held at the Palm Springs Convention Center – 277 N. Avenida Caballeros –Palm Springs, CA 92262. Register for ACT Join EPL at Our Hosted Program: “All About
Meet EPL and Aclairo at the 38th Annual ACT in Booth #200 Read More »
