Author name: kcahill@epl-inc.com

Reading Time: < 1 minuteMeet the professionals from EPL and Aclairo at the SOT 57th Annual Meeting and ToxExpo in San Antonio, Texas from March 11-15 in Booth #922. Register Now https://gallery.mailchimp.com/ac4f9b280cf9318f92a974f7f/images/2bae830e-b513-490d-b566-0d81955f4d5a.png https://gallery.mailchimp.com/ac4f9b280cf9318f92a974f7f/images/ddd85845-8d13-4be5-8019-c58db4a108b9.png About EPLFounded in 1971, Experimental Pathology Laboratories, Inc. (EPL®) is a private, employee-owned U.S. company that is recognized internationally for its ability to meet the needs of the scientific community and the […]

Reading Time: < 1 minuteExperimental Pathology Laboratories, Inc. (EPL) announces a new strategic alliance with Quality Scientific Solutions, LLC (QS3). This alliance is targeted to provide EPL’s preclinical pathology expertise as an important resource to QS3. About Quality Scientific SolutionsQuality Scientific Solutions, LLC is a research and consulting company dedicated to helping clients create products that meet the highest standard

Reading Time: 2 minutesExperimental Pathology Laboratories, Inc. (EPL) is an independent, private, employee-owned company that is recognized internationally for its ability to meet the needs of the scientific community and the challenges of preclinical safety testing and development with high quality histopathology services.  EPL was founded in 1971, and became an employee-owned company in 1992.  EPL is proud

Reading Time: 2 minutesExperimental Pathology Laboratories, Inc. (EPL) and Aclairo Pharmaceutical Development Group, Inc. (Aclairo) are excited to announce that Dr. Heath Thomas has joined Aclairo as President and Senior Consultant. Dr. Thomas is a board-certified veterinary pathologist with over 20 years of experience in drug development from time spent with SmithKline Beecham, DuPont Pharmaceuticals, and GlaxoSmithKline, as

Reading Time: 3 minutesSince 2005 the US Food and Drug Administration (FDA) has required the evaluation of a new molecular entity in a thorough QT (TQT) study, which is intended to determine a drug’s effect on the QT interval.  The QT interval represents the duration of ventricular depolarization and subsequent cardiac repolarization, measured from the beginning of the

Reading Time: 2 minutesThe goal of this discussion is to help one understand and address the Food and Drug Administration’s Guidance for Industry, “Assessment of Abuse Potential of Drugs” Drug abuse is the intentional, non-therapeutic use of a drug or substance to achieve a desired psychological or physiological effect.  Abuse potential is a characteristic of a drug that

Reading Time: 3 minutesThe use of Transmission Electron Microscopy (TEM) in preclinical studies has significantly waned in the last 20 or so years.  There are multiple reasons for this.  TEM is expensive and labor intensive.  Compared to standard histopathology, TEM requires significantly more time and money to analyze samples.  The cost of maintaining an electron microscope is practical

Reading Time: 3 minutesA quality histological slide contains tissue that was properly sampled, fixed, processed, embedded, microtomed, and stained without artifacts. The production of a quality slide requires work be conducted according to the highest standards during each phase of histologic processing. The first and most important steps are precise necropsy techniques (e.g., postmortem interval, tissue sample size

Reading Time: 3 minutesIt is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed. Most situations are readily managed, but in rare

Reading Time: 3 minutesKerry Crabb, HTL(ASCP), is the Manager of North Carolina Laboratory Operations at EPL. Kerry joined EPL in 2015, and brought with him over 25 years of experience in managing histology laboratories. Kerry’s experience at both large pharmaceutical and agrochemical companies gave him a broad knowledge on some of the best practices related to histology and