Author name: kcahill@epl-inc.com

Reading Time: < 1 minuteImagine a group of great scientists and all around nice folks who worked with another group for years in dovetailed projects for their clients. It does not take much imagination to wonder why these folks would want to be in one happy group together.  On January 1, 2016, EPL, Inc.  acquired Aclairo PDG, Inc. as […]

Reading Time: < 1 minuteEPL and Aclairo Combine Preclinical Services Expertise EPL is pleased to announce that it has acquired Aclairo Pharmaceutical Development Group, Inc. (Aclairo) which provides independent and objective nonclinical, regulatory, and clinical ADME/DMPK expert strategy and implementation to the pharmaceutical and drug device industries. “Aclairo’s team of industry and ex-FDA experts have developed a specialized consultancy

Reading Time: 3 minutesIt is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed.  Most situations are readily managed, but in rare

Reading Time: 3 minutesA quality histological slide contains tissue that was properly sampled, fixed, processed, embedded, microtomed, and stained without artifacts. The production of a quality slide requires that work be conducted according to the highest standards during each phase of histologic processing. The first and most important steps are precise necropsy techniques (e.g., postmortem interval, tissue sample

Reading Time: 2 minutesDrug-induced vascular injury (DIVI) is a major concern for development of new and novel therapies.  Efforts to identify biomarkers consistent with DIVI have not been successful, largely attributed to the complex nature of the vascular responses to injury and a lack of understanding of the mechanisms controlling these responses.  Recent publications on biomarkers of DIVI

Reading Time: 2 minutesExperimental Pathology Laboratories, Inc. (EPL) is pleased to announce that Dr. Valerie Barlow will be providing clinical pathology evaluation and consultation services for EPL. Dr. Valerie G. Barlow holds a DVM, a Master of Science and Ph.D., and is a Diplomate of the American College of Veterinary Pathologists (clinical pathology).  Dr. Barlow was born and

Reading Time: 4 minutesImmunohistochemistry (IHC) has become a routinely used methodology for investigative and diagnostic evaluations that utilizes antigen-antibody reactions to identify antigens within cells or tissues.  While antigens are usually proteins, other antigenic biological products can also be recognized by antibodies including carbohydrates, lipids, nucleic acids, and others.   The identification and localization of tissue antigens using IHC

Reading Time: 3 minutesExperimental Pathology Laboratories, Inc. (EPL) opened a Midwest facility on September 1, 2014.  This office is headed by Dr. Paul Snyder formerly a Professor at Purdue University.  The Midwest office is located in the Purdue Research Park at 1305 Cumberland Ave., West Lafayette, IN.  With this central location, Dr. Snyder will be able to provide local

Reading Time: < 1 minuteEPL is pleased to announce that electron microscopy services will be provided in conjunction with the Laboratory for Neurotoxicity Studies (LNS) at the Virginia-Maryland College of Veterinary Medicine at Virginia Tech in Blacksburg, VA. Operating under the Virginia-Maryland College of Veterinary Medicine GLP Program, the LNS is a fully GLP-compliant, state-of-the-art transmission electron microscopy laboratory that

Reading Time: 3 minutesThe role of the toxicologic pathologist is continuously evolving and becoming ever more complex, as novel tools are being developed to identify structural and biochemical changes that result from exposure to toxic substances, and elucidate mechanisms of action by which toxins may potentially impact animal and human health.  Recently, EPL has been working with ToxStrategies