Category: Discovery

Immunostaining Assay Optimization – Tackling Intrinsic Study Variables

Immunohistochemistry or Immunofluorescence (IHC/IF) is employed routinely for investigative and diagnostic evaluations of antigen-antibody interactions within cells or tissues. While most IHC/IF target antigens are proteins, other antigenic biological substrates can also be recognized by antibodies (e.g., carbohydrates, lipids, or nucleic acids). Accurate and reproducible results are achieved when procedures used to identify and localize […]

DiscoveryHistologyPathologySafety AssessmentToxicology

EPL – Independent and Employee-Owned

Experimental Pathology Laboratories, Inc. (EPL) is an independent, private, employee-owned company that is recognized internationally for its ability to meet the needs of the scientific community and the challenges of preclinical safety testing and development with high quality histopathology services.  EPL was founded in 1971, and became an employee-owned company in 1992.  EPL is proud […]

DiscoveryHistologyPathologySafety AssessmentToxicology

Aclairo Welcomes Dr. Heath Thomas as New President

Experimental Pathology Laboratories, Inc. (EPL) and Aclairo Pharmaceutical Development Group, Inc. (Aclairo) are excited to announce that Dr. Heath Thomas has joined Aclairo as President and Senior Consultant. Dr. Thomas is a board-certified veterinary pathologist with over 20 years of experience in drug development from time spent with SmithKline Beecham, DuPont Pharmaceuticals, and GlaxoSmithKline, as […]

Biological TestingClinical Pharmacology & ModelingDiscoveryPathologySafety AssessmentToxicology

Get to Know Aclairo

Aclairo® Pharmaceutical Development Group, Inc. is committed to delivering independent and objective nonclinical and regulatory advice to the pharmaceutical industry. Every member of Aclairo’s staff strives to provide our clients with superior advice, analysis, work product and program assistance. Aclairo’s unique experience and capabilities help our clients’ development programs succeed. Our senior consultants are experienced ex-FDA […]

Clinical Pharmacology & ModelingDiscoverySafety AssessmentToxicology

EPL to Exhibit at the 56th Annual Society of Toxicology (SOT) Meeting

EPL will once again be exhibiting at ToxExpo™ in Baltimore from March 13-15, 2017.  If you are attending the 56th Annual Society of Toxicology Meeting, please visit our teams from EPL and Aclairo; we will be exhibiting in Booth #2332. Please stop by and visit EPL if you are in Baltimore!  For more information about the SOT, […]

DiscoveryPathologySafety AssessmentToxicology

The Benefits of Entrusting Your Histopathology Services to EPL

Companies who outsource the histopathology component of their valuable studies need to know that the work will be performed to the highest quality standards, on time, and at competitive prices.  Although claims of quality are easily made, true quality can be a difficult metric to gauge.  So let’s look at the evidence. Unlike its few […]

Biological TestingDiscoveryHistologyPathologySafety AssessmentToxicology

EPL and Histion Form Strategic Alliance to Enhance Medical Device and Biomaterial Testing

EPL announces a newly formed strategic alliance with Histion, an Everett, Washington based preclinical laboratory specializing in GLP-compliant routine and specialty histology and evaluation services.  This alliance is specifically targeted to expand and enhance EPL’s and Histion’s capabilities to an ever expanding area of medical device and novel biomaterial testing.  Although Histion specializes in processing […]

Biological TestingDiscoveryHistologyPathologySafety Assessment

EPL, Inc. Opens a Northeast Office in Collegeville, Pennsylvania

Experimental Pathology Laboratories, Inc. (EPL®) established EPL Northeast on February 8, 2016. This office is headed by Dr. Heath Thomas who was formerly Vice President of Safety Assessment at GlaxoSmithKline. The Northeast office is located outside of Philadelphia at 125 Chinaberry Lane, Collegeville, PA. With this location, Dr. Thomas will be able to provide local […]

DiscoveryPathologySafety AssessmentToxicology

Meet Aclairo Pharmaceutical Development Group

Imagine a group of great scientists and all around nice folks who worked with another group for years in dovetailed projects for their clients. It does not take much imagination to wonder why these folks would want to be in one happy group together.  On January 1, 2016, EPL, Inc.  acquired Aclairo PDG, Inc. as […]

Clinical Pharmacology & ModelingDiscoverySafety AssessmentToxicology

The Benefits of Immunohistochemistry (IHC)

Immunohistochemistry (IHC) has become a routinely used methodology for investigative and diagnostic evaluations that utilizes antigen-antibody reactions to identify antigens within cells or tissues.  While antigens are usually proteins, other antigenic biological products can also be recognized by antibodies including carbohydrates, lipids, nucleic acids, and others.   The identification and localization of tissue antigens using IHC […]

Biological TestingDiscoveryHistologyPathologySafety Assessment