Category: Histology
A Closer Look at Ocular Toxicity Studies
The eye and the ocular adnexa are common target organs in toxicology studies, but the appropriate evaluation of ocular tissues is a specialized endeavor. Compared to routine toxicity studies, ocular toxicity studies require methodological modifications at almost every stage from study design to the final pathology report. EPL has extensive experience in the processing and […]
The Benefits of Entrusting Your Histopathology Services to EPL
Companies who outsource the histopathology component of their valuable studies need to know that the work will be performed to the highest quality standards, on time, and at competitive prices. Although claims of quality are easily made, true quality can be a difficult metric to gauge. So let’s look at the evidence. Unlike its few […]
EPL Announces New President
EPL is pleased to announce the promotion of Dr. Kathleen Funk to President of EPL on June 1, 2016. Dr. Funk has served as the Chief Operating Officer since 2014. Dr. Funk is a graduate of the Virginia-Maryland Regional College of Veterinary Medicine and also holds a PhD in Comparative Pathology from the University of […]
EPL and Histion Form Strategic Alliance to Enhance Medical Device and Biomaterial Testing
EPL announces a newly formed strategic alliance with Histion, an Everett, Washington based preclinical laboratory specializing in GLP-compliant routine and specialty histology and evaluation services. This alliance is specifically targeted to expand and enhance EPL’s and Histion’s capabilities to an ever expanding area of medical device and novel biomaterial testing. Although Histion specializes in processing […]
Experimental Pathology Laboratories, Inc. (EPL) Acquires Aclairo Pharmaceutical Development Group, Inc.
EPL and Aclairo Combine Preclinical Services Expertise EPL is pleased to announce that it has acquired Aclairo Pharmaceutical Development Group, Inc. (Aclairo) which provides independent and objective nonclinical, regulatory, and clinical ADME/DMPK expert strategy and implementation to the pharmaceutical and drug device industries. “Aclairo’s team of industry and ex-FDA experts have developed a specialized consultancy […]
On-Time Pathology Reporting
It is every client’s desire and expectation that their study report will be completed “On-Time” or better yet, be available ahead of schedule. There are a number of factors that determine whether a pathology report will be early, on time, or in the worst case scenario, delayed. Most situations are readily managed, but in rare […]
Histology Slide Quality
A quality histological slide contains tissue that was properly sampled, fixed, processed, embedded, microtomed, and stained without artifacts. The production of a quality slide requires that work be conducted according to the highest standards during each phase of histologic processing. The first and most important steps are precise necropsy techniques (e.g., postmortem interval, tissue sample […]
The Benefits of Immunohistochemistry (IHC)
Immunohistochemistry (IHC) has become a routinely used methodology for investigative and diagnostic evaluations that utilizes antigen-antibody reactions to identify antigens within cells or tissues. While antigens are usually proteins, other antigenic biological products can also be recognized by antibodies including carbohydrates, lipids, nucleic acids, and others. The identification and localization of tissue antigens using IHC […]
EPL Announces New Alliance for Electron Microscopy Services
EPL is pleased to announce that electron microscopy services will be provided in conjunction with the Laboratory for Neurotoxicity Studies (LNS) at the Virginia-Maryland College of Veterinary Medicine at Virginia Tech in Blacksburg, VA. Operating under the Virginia-Maryland College of Veterinary Medicine GLP Program, the LNS is a fully GLP-compliant, state-of-the-art transmission electron microscopy laboratory that […]
Ocular Toxicity Studies: Specialized Necropsy, Histology, and Pathology Methods
The eye and the ocular adnexa are common target organs in toxicology studies, but the appropriate evaluation of ocular tissues is a specialized endeavor. Compared to routine toxicity studies, ocular toxicity studies require methodological modifications at almost every stage from study design to the final pathology report. For example, at necropsy, the fragile nature of […]